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Recent Developed Ultrasensitive Methods for Ochratoxin a Detection Using Fluorescence Analyzer Devices and Aptasensors
Current Issue
Volume 5, 2018
Issue 1 (January)
Pages: 5-16   |   Vol. 5, No. 1, January 2018   |   Follow on         
Paper in PDF Downloads: 58   Since Mar. 24, 2018 Views: 1313   Since Mar. 24, 2018
Authors
[1]
Aloys Hitabatuma, State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi, P. R. China.
[2]
Yue-hong Pang, State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi, P. R. China.
[3]
Xiao-fang Shen, State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi, P. R. China.
Abstract
Mycotoxin are secondary metabolite of molds which can cause acute or chronic toxicological effects. One type of mold can produce different types of mycotoxin and its production is affected by various factors. Molds are easily to grow on food product like cereals, coffee, beans, nuts, vegetables and fruits. Also, mycotoxins are founded in commercialized processed product like bread, wine, milk, other milk product, beer, chocolate products and even in meet and meet product because during food processing mycotoxin cannot be eliminated. Especially, OTA is the most mycotoxin with the nephrotoxic, immunotoxic, teratogenic and carcinogenic effects. The International Agency for Research on Cancer (IARC) has classified OTA in 2B Group (possibly carcinogenic agent) The best way to protect consumers against mycotoxin effect is early food detection. In recent years, various methods have been introduced for detection of OTA. However, they are usually time-consuming, labor-intensive and expensive. Therefore, these parameters limited their usage. The emerging method of detection, aptasensor, has attracted more attention for OTA detection, due to distinctive advantages including high sensitivity, selectivity and simplicity. In this review, the new developed Fluorescence analyzer optical devices and aptasensors for detection of OTA have been investigated. We also highlighted advantages and disadvantages of different types of OTA detection methods. This review also takes into consideration the goal to find out which designed methods are the most rational ones for highly sensitive detection of OTA.
Keywords
Ochratoxin A, Aptasensors, Detection, Fluorescence Analysis, Colorimetrical, Electrochemical, Electrochemical
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