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Optical Digital Biopsy: Uveal Choroidal Melanoma: Case Report and Update of Technology
Current Issue
Volume 3, 2015
Issue 2 (April)
Pages: 59-63   |   Vol. 3, No. 2, April 2015   |   Follow on         
Paper in PDF Downloads: 9   Since Aug. 28, 2015 Views: 1325   Since Aug. 28, 2015
Authors
[1]
Zárate Jorge Oscar, Department of Pathology, Faculty of Medicine, Buenos Aires University (BAU), Buenos Aires, Argentina; Ophthalmic Research Laboratory and Vision Sciences, (BAU), Buenos Aires, Argentina; Digital Laboratory Pathology, Maimonides University, Buenos Aires, Argentina.
[2]
Pelayes David, Ophthalmic Research Laboratory and Vision Sciences, (BAU), Buenos Aires, Argentina; Digital Laboratory Pathology, Maimonides University, Buenos Aires, Argentina.
[3]
Folgar Martín, Ophthalmic Research Laboratory and Vision Sciences, (BAU), Buenos Aires, Argentina; Digital Laboratory Pathology, Maimonides University, Buenos Aires, Argentina.
[4]
Lacarta Guillermo, Digital Laboratory Pathology, Maimonides University, Buenos Aires, Argentina.
[5]
Alvarado Miguel, Digital Laboratory Pathology, Maimonides University, Buenos Aires, Argentina.
Abstract
Introduction: We report our initial observations on the technique of “optical digital biopsy” and its applications in a variety of diseases involving the vitreous, retina, retinal pigment epithelium, and choroid. In this case we present a patient with a diagnosis of intraocular choroidal tumors in which was replicated the optical digital biopsy with optimal results in our conclusions, confirmed later by enucleation. Optical Digital Biopsy is a noninvasive technique that allows the assessment of cellular composition and tissue, but the refinement of technique and additional validation studies are still necessary before being able to apply it clinically. This report includes an update of the technique and its possibilities.
Keywords
Optical Digital Biopsy, Intraocular Choroidal Tumors, Update
Reference
[1]
Zarate JO, Pelayes D, Singh A. Optical digital biopsy. A new method of tissue and cell identification with ophthalmic applications. Patología 2012; 50(3):179-181.
[2]
Wojtkowski M, Bajraszewski T, Gorczynska I, et al. Ophthalmic imaging by spectral optical coherence tomography. Am J Ophthalmol 2004; 138: 412.
[3]
Zárate JO. Optical Digital Biopsy. Brush strokes and pixels in the wonderful Latinamerican iconography. Patología 51(3):206-9.
[4]
Zárate JO. Digital optical biopsy. Possible extension to no other ophthalmic tissue. Patología Rev Latinoam 2014; 52:246-247.
[5]
Zarate JO, The pixelometría. New non-Euclidian geometry, biological importance. Phatology Latinoam Rev 2014 52: 143-145
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