The growth of endosymbiotic actinidic archaea in relation to climate change and global warming leads to neanderthalisation of the human mind-body system. Digoxin produced by archaeal cholesterol catabolism produces neanderthalisation. Digoxin produces intracellular magnesium deficiency and reverse transcriptase inhibition. This blocks retroviral replication and its integration into the genome. This reduces the flexibility and dynamicity of the genome. The inhibition of endogenous retroviral expression and integration by digoxin leads to atrophy of the prefrontal cortex. The cerebellum becomes dominant and can be considered as an endosymbiotic archaeal network. The cerebellar dominance leads to more of extrasensory perception, quantal perception, impulsive behaviour and sense of oneness with the world around us. The archaea contains magnetite and can catabolise cholesterol to generate porphyrins. Digoxin can produce sodium potassium ATPase inhibition and a pumped phonon system acting through dipolar magnetite and porphyrins to generate a Frohlich model of Bose-Einstein condensate and quantal perception. The prefrontal cortex atrophy can lead onto extinction of rationalization and reason producing a state of transcendence due to cerebellar dominance. This is the basis of surrealism. Actinidic archaeal related cerebellar dominance leads to changes in brain function. This produces a new sociopolitical, spiritual, sexual and cultural phenotype.

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