Welcome to Open Science
Contact Us
Home Books Journals Submission Open Science Join Us News Unsubscribe Page
New Releases
The Global Warming Related Epidemic Lemurian Glycolytic Syndrome - Glycolytic Renal, Cardiovascular, Pulmonary, Endocrine, Hepatic and Gastrointestinal Disease
Author:
Ravikumar Kurup,  Parameswara Achutha Kurup
ISBN: 978-1-941926-66-6
6.3 x 9.1 inches, 152pp, Paperback: $85
Published Date: July, 2016
To order hard copies, please contact book@openscienceonline.com
Introduction
Global warming leads to increase in endosymbiotic actinidic archaeal growth. Archaea are extremophiles. The actinidic archaea survive by catabolising cholesterol. The archaea and its antigens induce HIF alpha and activate the glycolytic pathway. The glycolytic pathway activation induces increased conversion of glucose to fructose by activation of the sorbitol pathway. Glucose is converted to sorbitol by the enzyme aldose reductase and sorbitol is converted to fructose by the action of sorbitol dehydrogenase. Fructose is phosphorylated by hexokinase or fructokinase to fructose phosphate. Hexokinase has a low km value for fructose and minimal amounts of fructose will be converted to fructose phosphate depleting the cellular ATP. ATP is converted to AMP and by the action of AMP deaminase is converted to uric acid. Thus there is resultant hyperuricemia and the depletion of ATP also produces membrane sodium potassium ATPase inhibition. Inhibition of membrane sodium potassium ATPase increases intracellular calcium and depletes magnesium. This produces cell death by opening up the mitochondrial PT pore, NFKB activation and immune activation, glutamate excitotoxicity and oncogene activation leading to systemic disorders. The depletion of ATP finally inhibits hexokinase as such and glucose phosphorylation stops blocking the glycolytic pathway and its coupling to the mitochondrial oxidative phosphorylation by the action of PT pore hexokinase. The cell is depleted of energy by glycolysis and the oxidative phosphorylation scheme and dies. Thus global warming via induction of glycolysis and Warburg phenotype and the increased conversion of glucose to fructose and the resultant cellular depletion of ATP can produce systemic disorders and cell dysfunction as well as death. This can produce the global warming related systemic syndrome.
Contents
The Full Book PDF PDF
Front Matter PDF
Chapter 1 Global Warming Related Systemic Syndrome PDF
Chapter 2 A Cholesterol and Actinide Dependent Shadow Biosphere of Archaea and Viroids in Chronic Renal Failure PDF
Chapter 3 A Cholesterol and Actinide Dependent Shadow Biosphere of Archaea and Viroids in Cardiovascular Disease PDF
Chapter 4 Actinidic Archaea and Viroids Related Hepato-Gastro-Intestinal Syndrome PDF
Chapter 5 A Cholesterol and Actinide Dependent Shadow Biosphere of Archaea and Viroids in Pulmonary Diseases PDF
Chapter 6 The Actinidic Archaea Related Lemurian Syndrome - Endomyocardial Fibrosis, Chronic Calcific Pancreatitis and Multinodular Goitre PDF
Chapter 7 Endemic Hyperdigoxinemia Related Cardiovascular and Endocrine Mucopolysaccharidoses Syndrome PDF
Chapter 8 Endosymbiotic Actinidic Archaea and Viroidal Induced Warburg Phenotype Can Be Reversed by a Modified Vegetarian High Fiber, High Medium Chain Triglyceride Ketogenic Diet PDF
Back Matter PDF
Author(s)
Ravikumar Kurup
Dr. Ravikumar Kurup trained in Internal Medicine, Neurology and Metabolic Medicine at Medical College, Trivandrum and Christian Medical College, Vellore. He holds a doctorate degree in Internal Medicine and Neurology. He is a member of the National Academy of Medical Sciences, India. He works as Professor of Metabolic Medicine and Metabolic Neurology at Metabolic Disorders Research Center, Trivandrum. He also works as Professor of Internal Medicine and Head of the divisions of Metabolic Medicine and Hematology at Medical College Hospital, Trivandrum. His areas of research interests are in Neurochemistry and Metabolic Medicine.
Parameswara Achutha Kurup
The Metabolic Disorders Research Centre, TC 4/1525, Gouri Sadan, Kattu Road North of Cliff House, Kowdiar PO Trivandrum, Kerala, India.
Readership
Experts in Neurology, Psychiatry, Internal Medicine
CONTACT US
Office Address:
228 Park Ave., S#45956, New York, NY 10003
Phone: +(001)(347)535 0661
E-mail:
LET'S GET IN TOUCH
Name
E-mail
Subject
Message
SEND MASSAGE
Copyright © 2013-2017, Open Science Publishers - All Rights Reserved