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Archaeal Cholesterol Catabolic Syndrome and Human Disease
Author:
Ravikumar Kurup,  Parameswara Achutha Kurup
ISBN: 978-1-941926-57-4
6.3 x 9.1 inches, 98pp, Paperback: $75
Published Date: June, 2016
To order hard copies, please contact book@openscienceonline.com
Introduction
Cholesterol is converted to bile acids by cholesterol 7 aplha hydroxylase in archaea and human cells. Bile acids can regulate metabolism, neuronal transmission and immunity. Bile acids bind to VDR receptor and downregulate the innate immune response. Bile acid deficiency leads to autoimmune disease. Bile acids bind to FXR receptor increasing glycogenesis, inhibiting gluconeogenesis and inhibiting triglyceride and VLDL synthesis. Thus bile acids can prevent metabolic syndrome x. Bile acids bind to the PXR receptor increasing cholesterol degradation. Blocking the PXR receptor produces cholesterol toxicity. Bile acids bind to TGR 5 receptor converting T4 to T3 and uncouple oxidative phosphorylation. T3 functions as a neurotransmitter in the cerebellar cortex and leads to dominance of unconscious brain function and CCAS. Bile acids also bind to olfactory receptors and stimulate the limbic lobe. Bile acid deficiency can lead to autism and schizophrenia. Thus the archaeal cholesterol catabolic syndrome can lead to cholesterol deficiency and bile acid deficiency. CoQ deficiency can lead to an autonomic neuropathy also contributing to metabolic syndrome, psychiatric disorders and autoimmune disease as well as neurodegenerations and malignancy.
Contents
The Full Book PDF PDF
Front Matter PDF
Chapter 1 Meditation Related Metabolonomic Changes - Endosymbiotic Actinidic Archaeal Cholesterol Catabolic Syndrome PDF
Chapter 2 Global Warming Induced Endosymbiotic Actinidic Archaeal Synthesis of Bile Acids from Cholesterol Regulates Cellular Function PDF
Chapter 3 Global Warming Induced Endosymbiotic Actinidic Archaeal Synthesis of PAH from Cholesterol Regulates Cell Function PDF
Chapter 4 Global Warming Induced Endosymbiotic Actinidic Archaeal Synthesis of Digoxin from Cholesterol Regulates Cellular Function and Contributes to Disease Pathology PDF
Chapter 5 Global Warming Induced Endosymbiotic Actinidic Archaeal Generation of Ammonia and Thiocyanate Regulates Cell/Neuro-Immuno-Endocrine System and Provides a Substrate for Archaeal Energetics PDF
Chapter 6 Global Warming Induced Endosymbiotic Actinidic Archaeal Synthesis of Pyruvate from Cholesterol and the GABA Shunt Pathway Regulates Cell Function PDF
Chapter 7 Global Warming Induced Endosymbiotic Actinidic Archaeal Synthesis of Short Chain Fatty Acid Butyrate and Propionate from Cholesterol Regulates Cellular Function PDF
Chapter 8 Global Warming Induced Endosymbiotic Actinidic Archaeal Synthesis of Neurotransmitters by Cholesterol Catabolism Regulates Brain Function PDF
Back Matter PDF
Author(s)
Ravikumar Kurup
Dr. Ravikumar Kurup trained in Internal Medicine, Neurology and Metabolic Medicine at Medical College, Trivandrum and Christian Medical College, Vellore. He holds a doctorate degree in Internal Medicine and Neurology. He is a member of the National Academy of Medical Sciences, India. He works as Professor of Metabolic Medicine and Metabolic Neurology at Metabolic Disorders Research Center, Trivandrum. He also works as Professor of Internal Medicine and Head of the divisions of Metabolic Medicine and Hematology at Medical College Hospital, Trivandrum. His areas of research interests are in Neurochemistry and Metabolic Medicine.
Parameswara Achutha Kurup
The Metabolic Disorders Research Centre, TC 4/1525, Gouri Sadan, Kattu Road North of Cliff House, Kowdiar PO Trivandrum, Kerala, India.
Readership
Experts in Neurology, Psychiatry, Philosophy
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