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Main Arteries Influence to Integral LDF-Signal Pattern
Current Issue
Volume 1, 2014
Issue 5 (September)
Pages: 34-36   |   Vol. 1, No. 5, September 2014   |   Follow on         
Paper in PDF Downloads: 18   Since Aug. 28, 2015 Views: 1409   Since Aug. 28, 2015
Petr Vasilev, The Department of Physiology, the Faculty of Medicine, Saint-Petersburg State University, Saint-Petersburg, Russia.
Nikolay Yerofeyev, The Department of Physiology, the Faculty of Medicine, Saint-Petersburg State University, Saint-Petersburg, Russia.
Nowadays there is a lot of research devoted to laser Doppler flowmetry (LDF). This method has high sensitivity, but absence of clear clinical application algorithms and result interpretation criteria are making difficulties in using of this method in clinical practice. The aim of our research was an investigation of the influence of the transducer position relative to the main arteries to the LDF-signal pattern. There were examined 10 healthy volunteers, at the age 18-20. Parameters of microcirculature were assessed through an LDF system Biopac LDF 100C (Biopac instruments, USA). It were registered a LDF-recording on the lower extremity, at the middle between points of pulsing of a. dorsalis pedis and a. tibialis posterior, and at the point of a. tibialis posterior pulsing, in a horizontal body position (on the back). After processing LDF-signals interesting phenomena were registered. In the case of transducer position in the middle between the arteries there are more expressed harmonics in amplitude-frequency spectrum, particularly, the sphygmic harmonic. Comparison between average amplitudes of the sphygmic harmonic above the artery and at the middle between the arteries are significally different (p<0.05) This phenomenon we connect to an influence of the bloodstream and transmitting pulsation of close main artery to LDF-signal pattern. It can be hypothesized that in those regions such pulsation becomes a significant factor of regional modulation of microcirculatory bloodstream. Less expression of the sphygmic harmonic in amplitude-frequency spectra of LDF signal, registered above the main arteries, can be explained by changes in histological structure of main arteries and the microcirculatory vessel wall. In the main artery, because of a lot of elastic elements in the wall, bloodstream has more regular character, without sharp overfalls. Because of that, bloodstream flow speed amplitudes, caused by sphygmic waves, in the main arteries are less than in microcirculatory arterioles, which wall is practically lacking of elastic elements. So, the contribution of the sphygmic wave to the bloodstream modulation is in inverse proportion with a quantity of non-crushing elements in the vascular wall. Because of that the optimal decision is putting the LDF-transducers much farther away from the projection lines of the main arteries.
Laser Doppler Flowmetry, Noninvasive Diagnostic Methods, Microvasculature, Main arteries, Study Protocol, Sphygmic Wave, LDF-Signal Pattern
N. P. Erofeev, Modern conception of the lymph flow physiology and treatment of lymphedema of the lower extremities. Saint-Petersburg, 2007, 154 p.
V. I. Konenkov, V. F. Prokofiev, A. V. Shevchenko, E. V. Zonova, “Cellular, vascular and extracellular components of the lymphatic system”. RAS newsletter #5 (133), 2008, pp. 7-13.
A. I. Krupatkin, V. V. Sidorov, Laser Doppler flowmetry of blood microcirculation. Moscow: Medicina, 2005, pp. 14-22.
A. I Krupatkin, V. V. Sidorov. Laser Doppler flowmetry of microcirculatory bloodstream. Guidelines for doctors. Moscow: Medicina, 2005. 125 p.
V. I. Kozlov, G. A. Azizov, O. A. Gurova, F.B. Lytwin. Laser Doppler flowmetrty in the appraisal of condition and dysfunctions microcirculatory bloodstream. Moscow: RUDN, SSC of laser medicine, 2012. 32 с.
L. V. Orlov, “Laser Doppler flowmetry in medical practice”. Kazan medical journal, vol. 83, #3, 2002, pp. 217-218.
V. I. Kozlov, G. A. Azizov, “Mechanism of modulation of the blood flow and its changes during essential arterial hypertension”, Regional Haemodynamics and Microcirculation, vol. 2, 2003, pp. 53-59.
S. G. Abramovich, A. V. Mashanskaya, “Laser Doppler flowmetry in estimation of microcirculation in healthy people and patients with arterial hypertension”. Siberian medical journal, #1, 2010, pp. 57-59.
M. S. Lubarskiy, Edemas of extremities. Novosibirsk, 2004, pp. 41-62.
L. V. Potashov, N. A. Bubnova, R. S. Orlov, A. V. Borisov, R. P. Borisova, S. V. Petrov. Surgical Lymphology. Saint-Petersburg, 2002, 273 p.
Al-Qaisi M., Kharbanda R.K., Mittal T.K., Donald A.E. Measurement of endothelial function and its clinical utility for cardiovascular risk // Vascular Health and Risk Management, 4 (3), 2008. 647-652 pp.
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