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Provoke of Viral Hepatitis on the Lipid Indices Among the Eastern Sudanese Patients
Current Issue
Volume 6, 2019
Issue 3 (September)
Pages: 32-36   |   Vol. 6, No. 3, September 2019   |   Follow on         
Paper in PDF Downloads: 12   Since Nov. 21, 2019 Views: 755   Since Nov. 21, 2019
Authors
[1]
Maisa Ahmed Badneen Maki, Department of Postgraduate Studies, Faculty of Medical Laboratory Sciences, Alzaiem Alazhari University, Khartoum, Sudan.
[2]
Bashir Abdrhman Bashir, Department of Hematology, Faculty of Medical Laboratory Sciences, Port Sudan Ahlia College, Port Sudan, Sudan.
[3]
Amna Othman Alzain, Department of Postgraduate Studies, Faculty of Medical Laboratory Sciences, Alzaiem Alazhari University, Khartoum, Sudan.
Abstract
Background: Globally, about 325 million people are surviving with hepatitis B virus (HBV) and hepatitis C virus (HCV) infection, with the highest infection rates of HBV recorded in Sudan. Despite the HBV or HCV infections linked to morbidity and mortality, the lipid indices could reflect the clinical course of liver impairment. Objective: This study elucidated the provoke of viral hepatitis on lipid indices among eastern Sudanese hepatitis patients. Material and Methods: Overnight fasting blood specimens were collected from HBV/HCV casualty patients who admitted to Port Sudan teaching hospital during March to July 2019. 80 subjects were enrolled in this work. 42 diagnosed with seropositive HBV or HCV, along with 38 healthy appearing adults as a control. Body mass index and lipid indices were determined. HBV and HCV were confirmed by enzyme linked immunosorbent assay (ELISA). Result: HBV was observed in 36 (45%) and HCV was noted in 6 (7.5%). Total cholesterol, triglyceride, very low-density lipoprotein-cholesterol (VLDL-c), low density lipoprotein-cholesterol (LDL-c), risk factor 2 index were significantly higher in patients with hepatitis, whereas high density lipoprotein-cholesterol (HDL-c) and risk factor 1 index were significantly lower in patients with viral hepatitis than in normal subjects (P < 0.000). Conclusion: HBV or HCV contributes to hyperlipidemia among eastern Sudanese populations. HDL-c and risk factor 1 index could be best evidence of liver trauma.
Keywords
Lipid Indices, Viral Hepatitis, HDL, Risk Factor, Port Sudan
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