Evaluation of Haemodialysis Adequacy Using Urea Reduction Ratio (URR) in Adult Patients with End Stage Renal Disease in Benin City
Mathias Abiodun Emokpae, Department of Medical Laboratory Science, School of Basic Medical Sciences, University of Benin, Benin City, Nigeria.
Prosper Omigie, Department of Chemical Pathology, University of Benin Teaching Hospital, Benin City, Nigeria.
The quality of haemodialysis is a predictor of mortality in patients with End Stage Renal Disease. The Urea Reduction Ratio (URR) is a simple and most popular method used in clinical practice to assess the effectiveness of delivered haemodialysis dose after a session of dialysis. This study evaluates the adequacy of haemodialysis dose in patients with end stage renal disease (ESRD). This is a cross sectional study of 52 patients with ESRD; 30 males (57.7%) and 22 females (42.3%) on maintenance haemodialysis. Pre-dialysis and post-dialysis blood specimens were collected; urea, creatinine and electrolytes were assayed by spectrophotometric technique and Ion Selective Electrode (ISE) analyzer respectively. The URR was calculated and used as a measure of haemodialysis adequacy. The URR of 61.0±3.2% was observed which is lower than URR of ≥65% recommended by the Kidney Disease outcome Quality Initiative guidelines. The data presented in this study indicate a lower haemodialysis adequacy in patients with ESRD. It is suggested that comprehensive approach may be adopted in order to achieve the recommended URR of ≥65%. The government should create more functional haemodialysis facilities and subsidize treatment so that every individual no matter the socioeconomic status can be treated.
End Stage Renal Disease, Haemodialysis Adequacy, Urea Reduction Ratio
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