On the Passive Exposure to Nicotine from Traditional Cigarettes Versus e-Cigarettes
This study reports on the measurement and comparison of passive exposures to nicotine from smokers/vapers of conventional and e-cigarettes, respectively. To this end, a smoking machine was constructed whose experimental conditions can be easily changed and in which the nicotine of the produced smoke or aerosol was trapped and further analyzed by HPLC. The main results of the present work were (a) the average value of nicotine delivered per puff, was 42 ± 0.3 μg/puff for the combustion cigarette and 25 ± 0.2 μg/puff for the e-cigarette (b) it was found a drastic reduction to nicotine exposure in the passive subject when the active smoker was replaced by the active vaper. Specifically, at a distance of 100 cm, the passive smoker reduced its exposure to nicotine from 600 ng/puff to five ng/puff when the active subject was vaping an e-cigarette. The main conclusion of the investigation was the drastic reduction to nicotine exposure of the passive subject with the use of the e-cigarettes. instead of conventional cigarettes by the active vaper or smoker, respectively. Finally the present study suggest that the nicotine exposure experienced by the passive subject may follow an inverse quadratic dependence with the distance from the active smoker or vaper.
HPLC, E-cigarette, Passive Smoking, Nicotine Exposure
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