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Formulation of Dynamic Buffer Capacity for Phytic Acid
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Volume 2, 2015
Issue 1 (February)
Pages: 5-9   |   Vol. 2, No. 1, February 2015   |   Follow on         
Paper in PDF Downloads: 29   Since Aug. 28, 2015 Views: 1439   Since Aug. 28, 2015
Anna Maria Michałowska-Kaczmarczyk, Department of Oncology, the University Hospital in Cracow, Cracow, Poland.
Tadeusz Michałowski, Department of Analytical Chemistry, Cracow University of Technology, Cracow, Poland.
Agustin G. Asuero, Department of Analytical Chemistry, the University of Seville, Seville, Spain.
The general formulation of dynamic buffer capacity for polyprotic acids and bases (and polyprotic acid and base salts) has been derived. Polyprotic acids show buffer capacity over a broad range of pH values, according to their successive protonation constants. Polyprotic acids with equidistant pKi values behave as universal buffers. The paper covers the dynamic buffer capacity for phytic acid, which posse’s twelve acid groups. Phytic acid, the hexaphosphate ester of myo-inositol, has a great biological relevance, and shows antioxidant/anticancer properties.
Acid-Base Equilibria, Buffer Capacity, Phytic Acid, Titration
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