Effects of Honey on Some Hematological Indices and Lipid Profile in Male Mice
[1]
Tende Joshua Adamu, Department of Human Physiology, Faculty of Basic Medical Sciences, College of Health Sciences, Ahmadu Bello University, Zaria, Nigeria.
[2]
Goji Anthony Donatus Teru, Department of Human Physiology, Faculty of Basic Medical Sciences, College of Medicine, Kaduna State University, Kaduna, Nigeria.
[3]
Odiase Imuentiyan David, Department of Human Physiology, Faculty of Basic Medical Sciences, College of Health Sciences, Ahmadu Bello University, Zaria, Nigeria.
[4]
Isah Anthony Denis, Department of Obstetrics and Gynaecology, University of Abuja Teaching Hospital, Abuja, Nigeria.
This study was designed to investigate the effect of acute administration of honey on some haematological and biochemical parameters in male mice. Fifteen male mice were divide into five groups of three each and were administered with distilled water, 10%, 20%, 50%, and 100% (v/v) of pure honey daily for seven days in that order. On the eighth day the mice were sacrificed and blood samples were collected for analyses. Total cholesterol, HDL, LDL, Triglyceride level and complete blood counts were determined by automatic analyzer. Low density lipoprotein (LDL) levels in mice treated with 10% (v/v), 20% (v/v), 50% (v/v) and 100% (v/v) showed an increase (p < 0.05) as compared to the control group, this was also observed in Total cholesterol levels. However, HDL levels in mice treated with 10% v/v, 50% v/v and 100% v/v were higher (p > 0.05) but 20% (v/v) was slightly lower as compared to the control group. Group 5 [100% (v/v)] was higher as compared to group 2 (10% v/v) and group 4 [50% (v/v)]. Triglyceride levels showed decrease (p > 0.05) in the rest of the group as compared to the control group. There was increase (p > 0.05) MID (monocyte count) with increasing concentration and increase in Platelet count in Group 2 [10% (v/v)] as compared to the other groups. Hb, PCV and RBCs Count were higher (p > 0.05) in Group 2 [10% (v/v)] as compared to the rest of the groups. Results from this study suggest that daily consumption of honey might have some positive effects on hematological indices and lipid profile respectively.
Honey, Lipid, Haematological, Lipoprotein, Mice
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